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CAS No. 119-75-5, chemically designated as 4-Amino-3-nitrobenzoic acid, constitutes a critical building block within the global fine chemicals value chain. Valued for its unique dual-functional configuration—containing both an amino group and a carboxyl group situated ortho to a nitro group—this molecule is extensively utilized in the synthesis of high-performance organic pigments, sophisticated pharmaceutical intermediates, and customized polymer matrices.
The global demand for 4-Amino-3-nitrobenzoic acid is driven by the expansion of precision pharmacology and structural materials. Across European and American manufacturing hubs, this molecule is recognized as a key pre-cursor for active pharmaceutical ingredients (APIs). Simultaneously, the booming industrial manufacturing landscape in the Asia-Pacific region has catalyzed massive integration of CAS No. 119-75-5 within robust dyestuffs production lines and specialized engineering plastics formulation.
As synthetic procedures become cleaner and more stringent regulations govern chemical waste, industrial purchasers favor manufacturers who maintain high-efficiency synthesis routes. To achieve reliable, high-yield product output, leading chemical suppliers like YANXA utilize state-of-the-art catalytic hydrogenation systems, minimizing structural isomeric contaminants such as 2-nitro and 3-nitro analogs.
HPLC Certified Purity Grades Available
Strict Manufacturing Compliance
Supply Chain Logistics Integration
Analyzing how different global industrial zones integrate 4-Amino-3-nitrobenzoic Acid (CAS No. 119-75-5) to optimize their specialized product output.
In North American and European biopharmaceutical clusters, 4-Amino-3-nitrobenzoic acid is an essential building block for targeted drugs. It provides the carbon-nitrogen scaffold required to construct complex heterocyclic systems, such as benzimidazoles, which form the base structures of several anti-arrhythmic and anti-hypertensive therapeutics.
For advanced aerospace and automotive materials, the nitro-functionalized benzoic acid acts as a modifying co-monomer. By introducing CAS 119-75-5, polymer manufacturers can synthesize modified polyimides and polyamides that exhibit superior thermal insulation properties and elevated glass transition temperatures.
In East Asian pigment production lines, this compound acts as a diazotization component in producing bright, light-fast organic red and yellow colorants. These pigments are highly demanded in automotive coatings, UV-curable printing inks, and consumer packaging materials due to their environmental stability.
A rigorous review of the chemical synthesis methodologies, purification technologies, and sustainability improvements for CAS No. 119-75-5.
Typically, 4-Amino-3-nitrobenzoic acid is produced through the controlled nitration of 4-aminobenzoic acid (PABA) using sulfuric acid and nitric acid mixtures. However, modern environmental expectations have driven factories to transition towards cleaner paths.
One prominent ecological synthesis pathway involves starting with 4-methyl-3-nitrobenzoic acid, followed by a selective catalytic oxidation step and subsequent conversion of the functional groups. Controlling reaction parameters like temperature, molar ratio, and catalyst dispersion is critical to reducing raw material loss and preventing unwanted isomer formation.
Analytical Quality Assessment: The final product is subject to rigorous testing. We verify purity through High-Performance Liquid Chromatography (HPLC) coupled with Mass Spectrometry (LC-MS) to ensure that the trace metal content and isomeric impurities remain below the threshold required by international pharmaceutical consortia.
The future of CAS No. 119-75-5 manufacturing lies in bio-based raw materials and continuous flow microreactors. Continuous flow systems permit precise control of the exothermic nitration process, reducing thermal degradation hazards and dramatically shrinking the environmental footprint. YANXA continues to invest in optimizing these technical routes to deliver consistent purity while lowering operational overhead.
| Parameters | Industrial Standard Limit |
|---|---|
| Appearance | Light Yellow Crystalline Powder |
| Assay (HPLC) | ≥ 99.0% (Ultrapure ≥ 99.5%) |
| Melting Point Range | 282 °C to 286 °C |
| Loss on Drying | ≤ 0.5% |
| Residue on Ignition | ≤ 0.2% |
| Heavy Metals | ≤ 20 ppm |
How Yanxatech (YANXA) bridges the gap between state-of-the-art raw material synthesis and uninterrupted global supply assurance.
Due to our deep structural links within major Chinese petrochemical clusters, YANXA secures uninterrupted raw feedstock access, bypassing localized supply blockages that halt production in smaller facilities.
Our partner factories strictly abide by the updated Chinese national environmental policies and safety mandates. Investing in advanced green treatment equipment ensures we do not experience forced regulatory shutdowns during strict inspection periods.
Located near vital transport conduits and ocean ports, we organize efficient cargo handovers. We provide multimodal shipping options (LCL, FCL, and dangerous goods transport) to guarantee timely deliveries to Europe, North America, and beyond.
Yanxatech System Industries Limited (hereinafter referred to as YANXA) is one of the growing suppliers in the field of specialty materials in China. Starting from a fledgling small business unit in 2008, YANXA is driven with the passion of developing a broad international market in the area relating to chemical and mechanical industries. Thanks to our team’s enduring and persistent work and our business partners’ long-lasting support, YANXA has steadily and vigorously grown into a company with excellence in delivering products and services relating to specialty chemicals.
Cooperating with leading manufacturers and renowned research institutes in the field of specialty chemicals in China, YANXA is capable of supplying:
Our Business Philosophy: Quality, safety, and efficiency prevail over all other values in our business. We care about what our customers need regarding general products as well as their unique and specific requirements for newly developed applications in a timely manner. We adhere strictly to technical requirements and make deliveries in almost perfect conformity. Because chemical businesses expose more safety concerns than other industrial sectors, we undertake all activities involving chemicals in a safe way to ensure the safety of human health and the environment.
Retaining direct specifications for our legacy chemical products and established customer lines.
Product Characteristics: Formaldehyde is a colorless liquid, easily polymerized, and readily soluble in water, alcohol, and ether. It is rapidly oxidized to formic acid in air, acting as a strong reducing agent. Its boiling point is -19°C, freezing point -118°C, and relative density to air is 1.067. Commercially, it is supplied in liquid form as formalin, a 37-50% formaldehyde solution with a small amount of methanol added as a polymerization inhibitor. The solution is milky white and has a foul odor. Formalin readily vaporizes, releasing formaldehyde gas. Its boiling point is 96°C, relative density is 0.815/-20°C, and flash point is 55°C.
Product Overview: Hexamethylenetetramine, also known as hexamine or HMTA, is a white crystalline powder produced by the condensation reaction of formaldehyde and ammonia. It is a versatile organic chemical intermediate widely used in industrial manufacturing, pharmaceutical synthesis, rubber processing, and analytical chemistry.
Product Features: A white powdery solid with a flammable odor of formaldehyde. It is a linear polymer of formaldehyde with no fixed melting point.
| Item Specifications | Standard Grade | High Grade |
|---|---|---|
| Appearance | White powder/solid | White powder/solid |
| Content | ≥ 92% | ≥ 96% |
| Solubility | ≤ 40 minutes | ≤ 40 minutes |
| Formic acid | ≤ 0.05% | ≤ 0.05% |
| pH | 5 - 7 | 5 - 7 |
Ensuring cross-border chemical movements comply with rigorous toxic chemical handling frameworks worldwide.
We supply completely localized Safety Data Sheets (SDS) and Globally Harmonized System (GHS) labels in the target market's language (including English, German, French, and Spanish). This ensures complete regulatory clarity during domestic transit and laboratory handling.
YANXA cooperates with authorized representatives to handle European REACH registration documentation, TSCA declarations in the US, and national chemical inventories in target countries, ensuring smooth customs processing without legal delay.
To preserve purity and guarantee safety, we package our products in UN-approved UN-rated fiber drums with moisture-barrier double-polyethylene liners. Inert gas purging options are also available for highly sensitive compounds.
Comprehensive responses to frequently asked questions regarding our chemical products, quality parameters, pricing, and logistic frameworks.
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