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A comprehensive analysis of PEG 300 synthesis, critical quality attributes, and strategic utilization in specialized sectors.
Polyethylene Glycol 300 (PEG 300) is a low molecular weight oligomer of ethylene oxide. Characterized by the chemical formula H(OCH₂CH₂)nOH, where the average value of n is approximately 6, this clear, viscous, and hygroscopic liquid offers exceptional physical-chemical properties. Thanks to its low polydispersity and highly stable ether linkages, PEG 300 functions as a versatile solvent, chemical intermediate, humectant, and polymer matrix modifier.
In high-performance industrial and pharmaceutical applications, the molecular weight distribution (MWD) of PEG 300 must be rigorously controlled. Even slight shifts in polydispersity can severely impact the viscosity, freezing point, and solubility characteristics of final formulations. YANXA partners with leading Chinese synthesis facilities utilizing advanced catalytic ethoxylation to produce PEG 300 with an incredibly tight MWD, ensuring batch-to-batch consistency and predictable formulation behavior.
High-purity PEG 300 must meet rigorous quality indicators. The table below highlights the standard physical and chemical metrics for PEG 300 supplied by YANXA, tailored to meet stringent regulatory limits.
| Test Parameter | Standard Specification Range | Testing Methodology (Typical) |
|---|---|---|
| Appearance | Clear, colorless viscous liquid, free from suspended matter | Visual inspection |
| Average Molecular Weight | 285 – 315 g/mol | Hydroxyl value calculation |
| Hydroxyl Value | 356 – 394 mg KOH/g | Ph. Eur. / USP titration |
| Water Content | ≤ 0.50% (Typically < 0.2%) | Karl Fischer titration |
| pH (5% Aqueous Solution) | 4.5 – 7.5 | Potentiometric measurement |
| Viscosity (at 20°C) | 75 – 85 mPa·s | Rotational viscometer |
| Residual Ethylene Oxide | ≤ 1 ppm (For pharma grade) | Headspace Gas Chromatography |
| Residual 1,4-Dioxane | ≤ 10 ppm (For pharma grade) | Headspace Gas Chromatography |
Integrating chemical raw material superiority with absolute quality control, international logistics reliability, and E-E-A-T principles.
Yanxatech System Industries Limited (hereinafter referred to as YANXA) is one of the growing suppliers in the field of specialty materials in China. Starting from a fledgling small business unit in 2008, YANXA is driven by a passion to develop a broad international market in areas relating to the chemical and mechanical industries. Thanks to our team’s enduring, persistent work and our business partners’ long-lasting support, YANXA has steadily and vigorously grown into an industry leader, delivering excellent products and services in specialty chemicals.
Cooperating with leading manufacturers and renowned research institutes in the specialty chemicals sector in China, YANXA is fully capable of supplying:
Quality, safety, and efficiency prevail over all other values in our business. We care deeply about what our customers need—both in terms of general product specifications and their unique, specific requirements for newly developed applications—and deliver solutions in a timely manner. We adhere strictly to technical requirements and achieve delivery in near-perfect conformity with customer parameters.
The chemical business inherently exposes safety concerns more complex than other industrial sectors. At YANXA, we undertake all activities involving chemicals in an environmentally responsible, safe way to protect human health and the natural environment. Our ISO9001:2008-certified processes guarantee systematic tracking and risk assessment throughout the production, packaging, and shipping stages.
Procuring Polyethylene Glycol 300 from a China manufacturer like YANXA unlocks significant supply chain advantages. China’s petrochemical industry boasts unparalleled integration, with direct pipelines from ethylene oxide production hubs to ethoxylation reactors. This proximity mitigates thermal and transport risks, stabilizes chemical supply, and dramatically reduces raw material costs.
Furthermore, our manufacturing sites are strategically located near major deep-water ports (Shanghai, Qingdao, and Tianjin), enabling efficient maritime logistics. With robust raw material sourcing, scale-based cost efficiencies, and optimized cargo routing, we offer highly competitive quotes while maintaining strict compliance with global standards, including REACH, FDA, and EU Pharmacopoeia limits.
From bio-pharma excipients to heavy industrial metal binders—how PEG 300 adapts to diverse localization needs.
In the pharmaceutical sector, PEG 300 is widely utilized as a co-solvent and excipient for liquid oral preparations, soft gelatin capsules, and ophthalmic formulations. Its low toxicity and high water solubility make it ideal for delivering poorly soluble active pharmaceutical ingredients (APIs).
For cosmetics and personal care formulations, it acts as a humectant and viscosity modifier. In regions with strict regulatory frameworks (such as the EU under REACH or North America under the FDA), we provide specialized, ultra-purified PEG 300 with guaranteed low limits on ethylene oxide, diethylene glycol, and 1,4-dioxane, satisfying all local health and safety standards.
PEG 300 is an outstanding binder and plasticizer in ceramic processing and metal powder metallurgy. In the production of atomized alloy powders, it prevents agglomeration and assists in green-body formulation during molding processes.
Its thermal stability allows clean burn-off during sintering, leaving zero ash residues. Additionally, it serves as a high-performance chemical intermediate in the synthesis of PEG esters, which are widely used as surfactants, emulsifiers, and industrial paper coatings.
Procuring industrial chemicals internationally demands comprehensive regulatory compliance. Every batch of PEG 300 shipped from YANXA’s partner facilities is accompanied by detailed Documentation Packs. These include Certificates of Analysis (COA), Safety Data Sheets (SDS) in accordance with the Globally Harmonized System (GHS), and certificates verifying compliance with local importing regulations (such as US FDA DMF, European REACH registration, and country-specific environmental standards).
Additionally, we provide customizable packaging solutions to adapt to local handling conditions. Whether your facility is optimized for standard 200kg steel drums, 1000kg Intermediate Bulk Containers (IBCs), or high-volume ocean transport using flexitanks, we customize the container type, sealing technology, and environmental barriers to preserve raw material purity.
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